This formula is especially helpful for those with genetic weaknesses in A01C (Diamine Oxidase), the main enzyme responsible for the degradation of ingested histamine. The active ingredient in G.I. Hist Support is porcine-derived diamine oxidase, and research suggests that DAO derived from porcine kidney appears to have identical action to DAO derived from porcine intestine. Common symptoms of histamine intolerance include:
An impaired histamine degradation based on reduced A01C (Diamine Oxidase) activity and the resulting histamine excess may cause numerous symptoms mimicking an allergic reaction. The ingestion of histamine-rich food or of alcohol or drugs that release histamine or block diamine oxidase may provoke stomach issues, headache, flushing and other conditions in patients with histamine intolerance. Diamine oxidase from porcine kidney may help assist with these types of issues.
Histamine is not only produced in the body but is also present in many fermented foods, such as sauerkraut, sausage, cheese, yogurt, and alcoholic beverages. Tuna, olives, spinach, eggplant, avocados, tomatoes, cherries, and citrus fruits are other histamine-containing foods which may cause GI irritation or histamine related reactions.
Porcine Kidney: The active ingredient in G.I. Hist Support is porcine kidney derived diamine oxidase, and research suggests that DAO derived from porcine kidney appears to have identical action to DAO derived from porcine intestine.*
Stinging Nettles: Studies have shown stinging nettles, through clinical results, has demonstrated promising mechanisms for supporting nasal passageway health. While further study is needed, trials have shown stinging nettles showed measurable differences vs. placebo after only one week.*
Bromelain: A pineapple enzyme, bromelain has proven mucolytic properties. As such, bromelain supports normal mucousal tissue function and enhances the absorption of quercetin.*
Quercetin: Quercetin acts as an antioxidant, neutralizing free radicals—the chemical by-products that harm cell membranes and damage DNA. Available as a dietary supplement, quercetin also possesses histamine and inflammatory reduction properties. Quercetin supports allergy sufferers by helping stabilize mast cell membranes that store and release histamine* NOTE: G.I. Hist Support does not manage or address antibody-related or IgE-related food allergies.
Directions: Adults take 1-2 capsules no more than 15 minutes before the consumption of histamine-rich foods. Children take one capsule no more than 15 minutes before the consumption of histamine-rich foods or take as directed by your healthcare practitioner.
As a daily maintenance support product, take 2 capsules in AM and 2 capsules in PM.
STORAGE: Keep lid tightly closed and in cool, dry area.
This product is not intended to treat, diagnose, or cure any disease. These statements have not been evaluated by the FDA.*
Serving Size: 2 Vegetable Capsules
Servings Per Container: 30
Amount Per Serving / % Daily Value:
Vitamin C (as ascorbic acid) 200 mcg / 222%
N Acetyl Cysteine 100 mg
Porcine Kidney powder 300 mg
Alpha Lipoic Acid 100 mg
Stinging Nettle (Urtica dioica) Root 4:1 50 mg
-Extract (Equivalent to 200 mg of Stinging Nettle)
Bromelain 100 mg
Other Ingredients: Vegetable cellulose (capsule), microcrystalline cellulose, ascorbyl palmitate and silicon dioxide.
Contains No: Wheat, gluten, yeast, soy, dairy products, fish, shellfish, peanuts, tree nuts, egg, ingredients derived from genetically modified organisms (GMOs), artificial colors, artificial sweeteners, or artificial preservatives.
If you are pregnant, nursing, taking any medication, have a medical condition, or planning any medical procedure, please consult your healthcare practitioner before taking any dietary supplement.